Gene
LZTS2
leucine zipper tumor suppressor 2
Explore in graph →CI-GENE-00011776HGNC:29381 ENSG00000107816 NCBI 84445 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26437033
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Fibroepithelial Tumors (Duke-NUS, Nat Genet 2015) bfn_duke_nus_2015 | Breast Fibroepithelial Neoplasm | Ssm | 1 | 22 | 4.5% | 148 | cbioportal |
| Pleural Mesothelioma (NYU, Cancer Res 2015) plmeso_nyu_2015 | Pleural Mesothelial Neoplasm | Ssm | 1 | 22 | 4.5% | 199 | cbioportal |
| Liposarcoma (MSK, 2026) lipo_msk_2026 | Liposarcoma | Ssm | 2 | 277 | 0.7% | 137 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.