Gene
LAMC1
laminin subunit gamma 1
Explore in graph →CI-GENE-00007557HGNC:6492 ENSG00000135862 NCBI 3915 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24487277
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (IRC, Nat Genet 2014) ccrcc_irc_2014 | Clear Cell Renal Cell Carcinoma | Ssm | 8 | 78 | 10.3% | 145 | cbioportal |
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 6 | 75 | 8% | 189 | cbioportal |
| Medulloblastoma (Sickkids, Nature 2016) mbl_sickkids_2016 | Medulloblastoma | Ssm | 3 | 46 | 6.5% | 38 | cbioportal |
| Combined Hepatocellular and Intrahepatic Cholangiocarcinoma (Peking University, Cancer Cell 2019) hccihch_pku_2019 | Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Ssm | 7 | 173 | 4% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.