Gene
KRT8
keratin 8
Explore in graph →CI-GENE-00007183HGNC:6446 ENSG00000170421 NCBI 3856 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 31852831
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Brain Tumor PDXs (Mayo Clinic, Clin Cancer Res 2020) gbm_mayo_pdx_sarkaria_2019 | Diffuse Glioma | Ssm | 15 | 105 | 14.3% | 158 | cbioportal |
| Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga | Adrenal Cortical Carcinoma | Ssm | 8 | 90 | 8.9% | 116 | cbioportal |
| Pediatric Pan-cancer (Columbia U, Genome Med 2016) mixed_pipseq_2017 | unmapped | Ssm | 8 | 103 | 7.8% | 195 | cbioportal |
| Prostate Adenocarcinoma (Broad/Cornell, Cell 2013) prad_broad_2013 | Prostate Adenocarcinoma | Ssm | 3 | 57 | 5.3% | 29 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.