Gene
KMT5B
lysine methyltransferase 5B
Explore in graph →CI-GENE-00007126HGNC:24283 ENSG00000110066 NCBI 51111 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22495314
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Invasive Carcinoma (British Columbia, Nature 2012) brca_bccrc | Invasive Breast Carcinoma | Ssm | 2 | 65 | 3.1% | 141 | cbioportal |
| Acute Myeloid Leukemia (TARGET GDC, 2025) aml_target_gdc | Acute Myeloid Leukemia | Ssm | 6 | 584 | 1% | 41 | cbioportal |
| Prostate Adenocarcinoma (CPC-GENE, Nature 2017) prad_cpcg_2017 | Prostate Adenocarcinoma | Ssm | 4 | 477 | 0.8% | 68 | cbioportal |
| Neuroblastoma (TARGET GDC, 2025) nbl_target_gdc | Neuroblastoma | Ssm | 3 | 471 | 0.6% | 115 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.