Gene
KLHL7
kelch like family member 7
Explore in graph →CI-GENE-00007042HGNC:15646 ENSG00000122550 NCBI 55975 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29625048,29596782,29622463,29617662,29625055,29625050,29617662,32214244,29625049,29850653,36334560
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Acute Myeloid Leukemia (TCGA, PanCancer Atlas) laml_tcga_pan_can_atlas_2018 | Acute Myeloid Leukemia | Ssm | 5 | 200 | 2.5% | 63 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, PanCancer Atlas) pcpg_tcga_pan_can_atlas_2018 | unmapped | Ssm | 2 | 178 | 1.1% | 78 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Cell 2017) pcpg_tcga_pub | unmapped | Ssm | 2 | 178 | 1.1% | 141 | cbioportal |
| Miscellaneous Neuroepithelial Tumor (TCGA GDC, 2025) mnet_tcga_gdc | Central Nervous System Neuroepithelial Neoplasm of Uncertain Origin | Ssm | 2 | 183 | 1.1% | 61 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.