Gene
ITGAL
integrin subunit alpha L
Explore in graph →CI-GENE-00006420HGNC:6148 ENSG00000005844 NCBI 3683 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25096233
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Bladder Urothelial Carcinoma (DFCI/MSK, Cancer Discov 2014) blca_dfarber_mskcc_2014 | Bladder Urothelial Carcinoma | Ssm | 5 | 50 | 10% | 112 | cbioportal |
| Myoepithelial Carcinomas of Soft Tissue (WCM, CSH Molecular Case Studies 2022) stmyec_wcm_2022 | Malignant Myoepithelioma | Ssm | 1 | 12 | 8.3% | 52 | cbioportal |
| Thyroid Carcinoma (TCGA, Firehose Legacy) thca_tcga | Thyroid Gland Papillary Carcinoma | Ssm | 4 | 405 | 1% | 40 | cbioportal |
| Papillary Thyroid Carcinoma (TCGA, Cell 2014) thca_tcga_pub | Thyroid Gland Papillary Carcinoma | Ssm | 4 | 496 | 0.8% | 39 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.