Gene
ITGA1
integrin subunit alpha 1
Explore in graph →CI-GENE-00006399HGNC:6134 ENSG00000213949 NCBI 3672 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 27634761
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Cancer (SMC, Cancer Research 2016) lung_smc_2016 | unmapped | Ssm | 5 | 22 | 22.7% | 53 | cbioportal |
| Insulinoma (Shanghai, Nat Commun 2013) panet_shanghai_2013 | Pancreatic Neuroendocrine Tumor | Ssm | 1 | 10 | 10% | 16 | cbioportal |
| Metastatic Breast Cancer (DFCI, Cancer Discov 2020) brca_dfci_2020 | Invasive Breast Carcinoma | Ssm | 4 | 59 | 6.8% | 94 | cbioportal |
| Prostate Adenocarcinoma (Broad/Cornell, Cell 2013) prad_broad_2013 | Prostate Adenocarcinoma | Ssm | 2 | 57 | 3.5% | 105 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.