Gene
IQSEC2
IQ motif and Sec7 domain ArfGEF 2
Explore in graph →CI-GENE-00006301HGNC:29059 ENSG00000124313 NCBI 23096 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Uterine Endometrioid Carcinoma (CPTAC GDC, 2025) uec_cptac_gdc | Endometrial Endometrioid Adenocarcinoma | Ssm | 31 | 247 | 12.6% | 105 | cbioportal |
| Endometrial Carcinoma (CPTAC, Cell 2020) ucec_cptac_2020 | Endometrial Carcinoma |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.