Gene
INVS
inversin
Explore in graph →CI-GENE-00006249HGNC:17870 ENSG00000119509 NCBI 27130 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29301960
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Clear Cell Renal Cell Carcinoma (DFCI, Science 2019) ccrcc_dfci_2019 | Clear Cell Renal Cell Carcinoma | Ssm | 2 | 35 | 5.7% | 155 | cbioportal |
| Adenoid Cystic Carcinoma (Sanger/MDA, JCI 2013) acyc_sanger_2013 | Adenoid Cystic Carcinoma | Ssm | 1 | 24 | 4.2% | 100 | cbioportal |
| Uveal Melanoma (QIMR, Oncotarget 2016) um_qimr_2016 | Uveal Melanoma | Ssm | 1 | 26 | 3.8% | 104 | cbioportal |
| Myelodysplastic (MSK, 2020) mds_mskcc_2020 | Myelodysplastic Syndrome | Ssm | 16 | 2,989 | 0.5% | 109 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.