Gene
IL21R
interleukin 21 receptor
Explore in graph →CI-GENE-00006083HGNC:6006 ENSG00000103522 NCBI 50615 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25201530
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Adenocarcinoma Organoids (MSK, Cell 2014) prad_mskcc_cheny1_organoids_2014 | Prostate Adenocarcinoma | Ssm | 2 | 12 | 16.7% | 74 | cbioportal |
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 3 | 29 | 10.3% | 172 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, Cancer Cell 2018) nsclc_mskcc_2018 | Lung Non-Small Cell Carcinoma | Ssm | 7 | 75 | 9.3% | 190 | cbioportal |
| High-Grade Serous Ovarian Cancer (TCGA GDC, 2025) hgsoc_tcga_gdc | High-Grade Serous Ovarian Cancer | Ssm | 9 | 405 | 2.2% | 164 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.