Gene
IL16
interleukin 16
Explore in graph →CI-GENE-00006060HGNC:5980 ENSG00000172349 NCBI 3603 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26855148
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Neuroendocrine Prostate Cancer (Multi-Institute, Nat Med 2016) nepc_wcm_2016 | Prostate Adenocarcinoma | Ssm | 4 | 114 | 3.5% | 142 | cbioportal |
| Diffuse Large B-Cell Lymphoma (Duke, Cell 2017) dlbcl_duke_2017 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 32 | 1,001 | 3.2% | 75 | cbioportal |
| Prostate Adenocarcinoma (MSK, Cancer Cell 2010) prad_mskcc | Prostate Adenocarcinoma | Ssm | 2 | 106 | 1.9% | 56 | cbioportal |
| Pilocytic Astrocytoma (ICGC, Nature Genetics 2013) past_dkfz_heidelberg_2013 | Pilocytic Astrocytoma | Ssm | 1 | 96 | 1% | 67 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.