Gene
IGSF3
immunoglobulin superfamily member 3
Explore in graph →CI-GENE-00005968HGNC:5950 ENSG00000143061 NCBI 3321 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (15)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33263939
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Juvenile Papillomatosis and Breast Cancer (MSK,J Pathol. 2015) brca_jup_msk_2020 | Invasive Breast Carcinoma | Ssm | 1 | 5 | 20% | 50 | cbioportal |
| Melanoma (Broad/Dana Farber, Nature 2012) skcm_broad_dfarber | Cutaneous Melanoma | Ssm | 5 | 26 | 19.2% | 103 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Mount Sinai 2015) ihch_ismms_2015 | Intrahepatic Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 56 | cbioportal |
| Kidney Renal Clear Cell Carcinoma (IRC, Nat Genet 2014) ccrcc_irc_2014 | Clear Cell Renal Cell Carcinoma | Ssm | 9 | 78 | 11.5% | 72 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.