Gene
HTR4
5-hydroxytryptamine receptor 4
Explore in graph →CI-GENE-00005257HGNC:5299 ENSG00000164270 NCBI 3360 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 37990009
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pediatric solid tumor PDXs (UTHSA, Nat Commun 2023) pancan_pdx_uthsa_2023 | unmapped | Ssm | 2 | 92 | 2.2% | 120 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Nature 2018) aml_ohsu_2018 | Acute Myeloid Leukemia | Ssm | 4 | 622 | 0.6% | 119 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Cancer Cell 2022) aml_ohsu_2022 | Acute Myeloid Leukemia | Ssm | 4 | 903 | 0.4% | 191 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.