Gene

HOXC10

homeobox C10

Curated evidence

Clinical evidence (2)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
HOXC10 Overexpression2
(prognostic)	Glioma	Prognostic	B	Supports Poor Outcome	4	submitted	EID10147 Public glioma datasets were analyzed from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus. HOXC10 was seen to be significantly elevated in gliomas compared to non-tumor brain tissues, a… (full text at CIViC) PMID 30429891 · Tan et al., 2018 · Open in CIViC	civic
Bevacizumab	Glioma	Predictive	D	Supports Sensitivity Response	3	submitted	EID9949 In determining the mechanisms of angiogenesis in gliomas, an in-depth preclinical analysis of HOXC10 overexpression in response to a vascular endothelial growth factor A (VEGFA) inhibitor bevacizumab … (full text at CIViC) PMID 30429891 · Tan et al., 2018 · Open in CIViC	civic

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

Data not yet available

No publication linked to this gene yet.