Gene
HLX
H2.0 like homeobox
Explore in graph →CI-GENE-00004508HGNC:4978 ENSG00000136630 NCBI 3142 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36001024
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 6 | 75 | 8% | 177 | cbioportal |
| Acute Lymphoblastic Leukemia - Phase III TARGET-ALL-P3 | Acute Lymphoblastic Leukemia | Ssm | 2 | 108 | 1.9% | 73 | gdc |
| Acute Leukemias of Ambiguous Lineage (TARGET GDC, 2025) alal_target_gdc | Acute Leukemia of Ambiguous Lineage | Ssm | 2 | 123 | 1.6% | 188 | cbioportal |
| Non-Seminomatous Germ Cell Tumor (TCGA GDC, 2025) nsgct_tcga_gdc | Non-Seminomatous Germ Cell Tumor | Ssm | 2 | 146 | 1.4% | 93 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.