Gene
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Explore in graph →CI-GENE-00004333HGNC:26072 ENSG00000138642 NCBI 55008 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24326773
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Insulinoma (Shanghai, Nat Commun 2013) panet_shanghai_2013 | Pancreatic Neuroendocrine Tumor | Ssm | 1 | 10 | 10% | 12 | cbioportal |
| Acute myeloid leukemia or myelodysplastic syndromes (WashU, 2016) mnm_washu_2016 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.