Gene
HELB
DNA helicase B
Explore in graph →CI-GENE-00004298HGNC:17196 ENSG00000127311 NCBI 92797 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33397444
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Upper Tract Urothelial Carcinoma (IGBMC, Genome Biology 2021) utuc_igbmc_2021 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 2 | 30 | 6.7% | 151 | cbioportal |
| Ovarian Cancer (CPTAC GDC, 2025) ovary_cptac_gdc | unmapped | Ssm | 4 | 95 | 4.2% | 136 | cbioportal |
| Prostate Adenocarcinoma (TCGA, PanCancer Atlas) prad_tcga_pan_can_atlas_2018 | Prostate Adenocarcinoma | Ssm | 6 | 494 | 1.2% | 194 | cbioportal |
| Neuroblastoma (AMC Amsterdam, Nature 2012) nbl_amc_2012 | Neuroblastoma | Ssm | 1 | 87 | 1.1% | 200 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.