Gene
H3C8
H3 clustered histone 8
Explore in graph →CI-GENE-00004014HGNC:4772 ENSG00000273983 NCBI 8355 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 39185963
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Atypical Small Cell Lung Cancer (MSK, Cancer Discov 2024) asclc_msk_2024 | unmapped | Ssm | 1 | 30 | 3.3% | 73 | cbioportal |
| Diffuse Large B-Cell Lymphoma (MSK, Haematologica 2024) mbn_msk_2024 | B-Cell Non-Hodgkin Lymphoma | Ssm | 13 | 396 | 3.3% | 85 | cbioportal |
| Glioma (MSK, Nature 2019) glioma_msk_2018 | Diffuse Glioma | Ssm | 2 | 91 | 2.2% | 189 | cbioportal |
| Nonmuscle Invasive Bladder Cancer (MSK Eur Urol 2017) blca_nmibc_2017 | Bladder Urothelial Carcinoma | Ssm | 2 | 103 | 1.9% | 184 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.