Gene
H3-5
H3.5 histone
Explore in graph →CI-GENE-00004005HGNC:33164 ENSG00000188375 NCBI 440093 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (11)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Sarcoma (MSK, 2026) lms_msk_2026 | unmapped | Ssm | 2 | 41 | 4.9% | 183 | cbioportal |
| IDH-mutated Diffuse Glioma (MSK, Clin Cancer Res 2024) difg_msk_2023 | Diffuse Glioma | Ssm | 2 | 73 | 2.7% | 77 | cbioportal |
| Rhabdomyosarcomas (MSK, NPJ Precis Oncol 2023) soft_tissue_msk_2023 | Rhabdomyosarcoma | Ssm | 1 | 42 | 2.4% | 30 | cbioportal |
| High-Grade Serous Ovarian Cancer (MSK, NPJ Genome Med 2021) hgsoc_msk_2021 | High-Grade Serous Ovarian Cancer | Ssm | 1 | 45 | 2.2% | 54 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.