Gene
GRM6
glutamate metabotropic receptor 6
Explore in graph →CI-GENE-00003650HGNC:4598 ENSG00000113262 NCBI 2916 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29657128
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Non-Small Cell Lung Cancer (MSK, Cancer Cell 2018) nsclc_mskcc_2018 | Lung Non-Small Cell Carcinoma | Ssm | 9 | 75 | 12% | 90 | cbioportal |
| Anaplastic Thyroid Cancers (GATCI, Cell Reports 2024) thyroid_gatci_2024 | unmapped | Ssm | 9 | 190 | 4.7% | 58 | cbioportal |
| Pancreatic Adenocarcinoma (QCMG, Nature 2016) paad_qcmg_uq_2016 | Pancreatic Adenocarcinoma | Ssm | 7 | 383 | 1.8% | 134 | cbioportal |
| Adenoid Cystic Carcinoma (MDA, Clin Cancer Res 2015) acyc_mda_2015 | Adenoid Cystic Carcinoma | Ssm | 1 | 65 | 1.5% | 187 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.