Gene
GREM1
gremlin 1, DAN family BMP antagonist
Explore in graph →CI-GENE-00003590HGNC:2001 ENSG00000166923 NCBI 26585 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Sarcoma (MSK, 2026) lms_msk_2026 | unmapped | Ssm | 3 | 41 | 7.3% | 111 | cbioportal |
| Primary CNS Lymphoma (MSK, Clin Cancer Res 2024) pcnsl_msk_2024 | Primary Central Nervous System Lymphoma | Ssm | 2 | 86 | 2.3% | 138 | cbioportal |
| Gallbladder Cancer (MSK, Cancer 2018) gbc_msk_2018 | Gallbladder Carcinoma | Ssm | 2 | 103 | 1.9% | 83 | cbioportal |
| Sarcoma (UCLA, Cell 2024) sarcoma_ucla_2024 | unmapped | Ssm | 1 | 63 | 1.6% | 147 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.