Gene
GLYR1
glyoxylate reductase 1 homolog
Explore in graph →CI-GENE-00003156HGNC:24434 ENSG00000140632 NCBI 84656 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33397444
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Upper Tract Urothelial Carcinoma (IGBMC, Genome Biology 2021) utuc_igbmc_2021 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 3 | 30 | 10% | 35 | cbioportal |
| Metastatic Pancreatic Adenocarcinoma (PRINCE Trial, Nat Med. 2022) - iAtlas Harmonized paad_iatlas_prince_2022 | Pancreatic Adenocarcinoma | Ssm | 4 | 93 | 4.3% | 141 | cbioportal |
| Glioblastoma Multiforme (TCGA GDC, 2025) gbm_tcga_gdc | Diffuse Glioma | Ssm | 16 | 377 | 4.2% | 40 | cbioportal |
| Kidney Renal Clear Cell Carcinoma (BGI, Nat Genet 2012) kirc_bgi | Clear Cell Renal Cell Carcinoma | Ssm | 1 | 98 | 1% | 152 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.