Gene
GCNA
germ cell nuclear acidic peptidase
Explore in graph →CI-GENE-00002861HGNC:15805 ENSG00000147174 NCBI 93953 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24265153
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Skin Cutaneous Melanoma(Broad, Cancer Discov 2014) skcm_broad_brafresist_2012 | Cutaneous Melanoma | Ssm | 14 | 78 | 17.9% | 158 | cbioportal |
| Colon Adenocarcinoma (CaseCCC, PNAS 2015) coad_caseccc_2015 | Colon Adenocarcinoma | Ssm | 2 | 29 | 6.9% | 162 | cbioportal |
| Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014 | Thymus Epithelial Neoplasm | Ssm | 1 | 32 | 3.1% | 185 | cbioportal |
| Pediatric Acute Lymphoid Leukemia - Phase II (TARGET, 2018) all_phase2_target_2018_pub | B Lymphoblastic Leukemia/Lymphoma | Ssm | 2 | 150 | 1.3% | 27 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.