Gene
GBP4
guanylate binding protein 4
Explore in graph →CI-GENE-00002830HGNC:20480 ENSG00000162654 NCBI 115361 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25488749
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pleural Mesothelioma (NYU, Cancer Res 2015) plmeso_nyu_2015 | Pleural Mesothelial Neoplasm | Ssm | 1 | 22 | 4.5% | 139 | cbioportal |
| Adenoid Cystic Carcinoma (JHU, Cancer Prev Res 2016) acyc_jhu_2016 | Adenoid Cystic Carcinoma | Ssm | 1 | 25 | 4% | 130 | cbioportal |
| Acute Myeloid Leukemia (TCGA, Firehose Legacy) laml_tcga | Acute Myeloid Leukemia | Ssm | 3 | 197 | 1.5% | 34 | cbioportal |
| Acute Myeloid Leukemia (TCGA, NEJM 2013) laml_tcga_pub | Acute Myeloid Leukemia | Ssm | 3 | 200 | 1.5% | 34 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.