Gene
GAK
cyclin G associated kinase
Explore in graph →CI-GENE-00002630HGNC:4113 ENSG00000178950 NCBI 2580 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33025139
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Schwannoma (Children's Tumor Foundation, Acta Neuropathologica 2020) schw_ctf_synodos_2025 | Schwannoma | Ssm | 6 | 40 | 15% | 80 | cbioportal |
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 11 | 116 | 9.5% | 181 | cbioportal |
| Breast Fibroepithelial Tumors (Duke-NUS, Nat Genet 2015) bfn_duke_nus_2015 | Breast Fibroepithelial Neoplasm | Ssm | 1 | 22 | 4.5% | 113 | cbioportal |
| Neuroblastoma (AMC Amsterdam, Nature 2012) nbl_amc_2012 | Neuroblastoma | Ssm | 1 | 87 | 1.1% | 174 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.