Gene
GAB2
GRB2 associated binding protein 2
Explore in graph →CI-GENE-00002554HGNC:14458 ENSG00000033327 NCBI 9846 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 7 | 19 | 36.8% | 166 | cbioportal |
| Atypical Small Cell Lung Cancer (MSK, Cancer Discov 2024) asclc_msk_2024 | unmapped | Ssm | 1 | 8 | 12.5% | 68 | cbioportal |
| Bladder Urothelial Carcinoma SWOG S1314 Trial (MSK, JCO Precis Oncol 2024) blca_msk_2024 | Bladder Urothelial Carcinoma | Ssm | 9 | 184 | 4.9% | 72 | cbioportal |
| Triple-Negative Breast Cancer (FUSCC, Cell Research 2020) brca_fuscc_2020 | Invasive Breast Carcinoma | Ssm | 2 | 69 | 2.9% | 89 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.