Gene
EXD3
exonuclease 3'-5' domain containing 3
Explore in graph →CI-GENE-00001106HGNC:26023 ENSG00000187609 NCBI 54932 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25765070
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Adenocarcinoma (MSK, Science 2015) luad_mskcc_2015 | Lung Adenocarcinoma | Ssm | 4 | 35 | 11.4% | 121 | cbioportal |
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 7 | 75 | 9.3% | 81 | cbioportal |
| Acute Lymphoblastic Leukemia (St Jude, Nat Genet 2016) all_stjude_2016 | B Lymphoblastic Leukemia/Lymphoma | Ssm | 1 | 73 | 1.4% | 176 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.