Gene
EIF2S3
eukaryotic translation initiation factor 2 subunit gamma
Explore in graph →CI-GENE-00044458HGNC:3267 ENSG00000130741 NCBI 1968 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (2)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29625048,29596782,29622463,29617662,29625055,29625050,29617662,32214244,29625049,29850653,36334560
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Acute Myeloid Leukemia (TCGA, PanCancer Atlas) laml_tcga_pan_can_atlas_2018 | Acute Myeloid Leukemia | Ssm | 4 | 200 | 2% | 100 | cbioportal |
| Adenoid Cystic Carcinoma (MDA, Clin Cancer Res 2015) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.