Gene
DVL2
dishevelled segment polarity protein 2
Explore in graph →CI-GENE-00044071HGNC:3086 ENSG00000004975 NCBI 1856 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33585982
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pediatric Low-Grade Glioma (CTF, Acta Neuropathol 2021) lgg_ctf_synodos_2025 | Diffuse Glioma | Ssm | 1 | 31 | 3.2% | 176 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Cell 2017) pcpg_tcga_pub | unmapped | Ssm | 2 | 178 | 1.1% | 106 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, Firehose Legacy) pcpg_tcga | Central Nervous System Neuroepithelial Neoplasm of Uncertain Origin | Ssm | 2 | 184 | 1.1% | 146 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.