Gene
DIO2
iodothyronine deiodinase 2
Explore in graph →CI-GENE-00043386HGNC:2884 ENSG00000211448 NCBI 1734 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24145436
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Mantle Cell Lymphoma (IDIBIPS, PNAS 2013) mcl_idibips_2013 | Mantle Cell Lymphoma | Ssm | 1 | 29 | 3.4% | 121 | cbioportal |
| Acute Myeloid Leukemia (TCGA GDC, 2025) aml_tcga_gdc | Acute Myeloid Leukemia | Ssm | 1 | 72 | 1.4% | 109 | cbioportal |
| Chronic Lymphocytic Leukemia (Broad, Cell 2013) lcll_broad_2013 | Small Lymphocytic Lymphoma | Ssm | 2 | 160 | 1.3% | 105 | cbioportal |
| Chronic Lymphocytic Leukemia (Broad, Nature 2015) cll_broad_2015 | Small Lymphocytic Lymphoma | Ssm | 5 | 537 | 0.9% | 135 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.