Gene
DEK
DEK proto-oncogene
Explore in graph →CI-GENE-00043228HGNC:2768 ENSG00000124795 NCBI 7913 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29033130
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Melanoma (MSK, Cell 2017) - iAtlas Harmonized mel_iatlas_riaz_nivolumab_2017 | Melanoma | Ssm | 9 | 73 | 12.3% | 100 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 3 | 38 | 7.9% | 189 | cbioportal |
| Urothelial Carcinoma (BCAN/HCRN, Nat Commun 2022) blca_bcan_hcrn_2022 | Bladder Urothelial Carcinoma | Ssm | 10 | 192 | 5.2% | 123 | cbioportal |
| Testicular Germ Cell Cancer (TCGA, Firehose Legacy) tgct_tcga | Non-Seminomatous Germ Cell Tumor | Ssm | 6 | 155 | 3.9% | 36 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.