Gene
DDR1
discoidin domain receptor tyrosine kinase 1
Explore in graph →CI-GENE-00043055HGNC:2730 ENSG00000204580 NCBI 780 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 27749842
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Urothelial Carcinoma (Cornell/Trento, Nat Gen 2016) blca_cornell_2016 | Bladder Urothelial Carcinoma | Ssm | 12 | 72 | 16.7% | 42 | cbioportal |
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 3 | 29 | 10.3% | 157 | cbioportal |
| Low-Grade Gliomas (UCSF, Science 2014) lgg_ucsf_2014 | Diffuse Glioma | Ssm | 6 | 61 | 9.8% | 31 | cbioportal |
| Mantle Cell Lymphoma (IDIBIPS, PNAS 2013) mcl_idibips_2013 | Mantle Cell Lymphoma | Ssm | 1 | 29 | 3.4% | 113 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.