Gene
CUL2
cullin 2
Explore in graph →CI-GENE-00042581HGNC:2552 ENSG00000108094 NCBI 8453 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32897884
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Germ Cell Tumors and Shared Leukemias (MSK, J Clin Invest 2020) gct_msk_2020 | unmapped | Ssm | 1 | 13 | 7.7% | 73 | cbioportal |
| Pediatric Low-Grade Glioma (CTF, Acta Neuropathol 2021) lgg_ctf_synodos_2025 | Diffuse Glioma | Ssm | 1 | 31 | 3.2% | 136 | cbioportal |
| Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014 | Thymus Epithelial Neoplasm | Ssm | 1 | 32 | 3.1% | 121 | cbioportal |
| Rhabdomyosarcoma (NIH, Cancer Discov 2014) rms_nih_2014 | Rhabdomyosarcoma | Ssm | 1 | 43 | 2.3% | 135 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.