Gene
CTNNA1
catenin alpha 1
Explore in graph →CI-GENE-00042510HGNC:2509 ENSG00000044115 NCBI 1495 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33067607
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lymphoma Cell Lines (MSK, Blood 2020) lymphoma_cellline_msk_2020 | unmapped | Ssm | 1 | 34 | 2.9% | 189 | cbioportal |
| Renal Cell Carcinoma (CPTAC GDC, 2025) rcc_cptac_gdc | Renal Cell Carcinoma | Ssm | 7 | 352 | 2% | 187 | cbioportal |
| Papillary Renal Cell Carcinoma (TCGA GDC, 2025) prcc_tcga_gdc | Papillary Renal Cell Carcinoma | Ssm | 5 | 279 | 1.8% | 173 | cbioportal |
| Kidney Renal Papillary Cell Carcinoma (TCGA, Firehose Legacy) kirp_tcga | Papillary Renal Cell Carcinoma | Ssm | 5 | 282 | 1.8% | 162 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.