Gene
CRB1
crumbs cell polarity complex component 1
Explore in graph →CI-GENE-00042186HGNC:2343 ENSG00000134376 NCBI 23418 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (53)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 21720365
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Ovarian Serous Cystadenocarcinoma (TCGA, Nature 2011) ov_tcga_pub | High-Grade Serous Ovarian Cancer | Ssm | 7 | 316 | 2.2% | 63 | cbioportal |
| Ovarian Serous Cystadenocarcinoma (TCGA, Firehose Legacy) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.