Gene
CNOT4
CCR4-NOT transcription complex subunit 4
Explore in graph →CI-GENE-00041752HGNC:7880 ENSG00000080802 NCBI 4850 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26862087
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (JHU, Cancer Prev Res 2016) acyc_jhu_2016 | Adenoid Cystic Carcinoma | Ssm | 1 | 25 | 4% | 76 | cbioportal |
| Pediatric Low-Grade Glioma (CTF, Acta Neuropathol 2021) lgg_ctf_synodos_2025 | Diffuse Glioma | Ssm | 1 | 31 | 3.2% | 119 | cbioportal |
| Renal Non-Clear Cell Carcinoma (Genentech, Nat Genet 2014) nccrcc_genentech_2014 | Renal Non-Clear Cell Carcinoma | Ssm | 3 | 146 | 2.1% | 72 | cbioportal |
| Neuroblastoma (AMC Amsterdam, Nature 2012) nbl_amc_2012 | Neuroblastoma | Ssm | 1 | 87 | 1.1% | 103 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.