Gene
CLCN5
Cl-/H+ antiporter 5
Explore in graph →CI-GENE-00041495HGNC:2023 ENSG00000171365 NCBI 1184 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Osteosarcoma (TARGET GDC, 2025) os_target_gdc | Osteosarcoma | Ssm | 3 | 143 | 2.1% | 29 | cbioportal |
| Renal Non-Clear Cell Carcinoma (Genentech, Nat Genet 2014) nccrcc_genentech_2014 | Renal Non-Clear Cell Carcinoma | Ssm | 3 | 146 | 2.1% | 71 | cbioportal |
| Pancreatic Adenocarcinoma (ICGC, Nature 2012) paad_icgc | Pancreatic Adenocarcinoma | Ssm | 2 | 99 | 2% | 59 | cbioportal |
| Renal Cell Carcinoma (CPTAC GDC, 2025) rcc_cptac_gdc | Renal Cell Carcinoma | Ssm | 7 | 352 | 2% | 181 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.