Gene
CFB
complement factor B
Explore in graph →CI-GENE-00041126HGNC:1037 ENSG00000243649 NCBI 629 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32042194
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| The Angiosarcoma Project - Count Me In (Nature Medicine, 2020) angs_project_painter_2018 | Angiosarcoma | Ssm | 5 | 48 | 10.4% | 52 | cbioportal |
| Cystic Tumor of the Pancreas (Johns Hopkins, PNAS 2011) pact_jhu_2011 | Pancreatic Mucinous Cystic Neoplasm | Ssm | 1 | 32 | 3.1% | 78 | cbioportal |
| Mesothelioma (TCGA, Firehose Legacy) meso_tcga | Pleural Mesothelial Neoplasm | Ssm | 2 | 87 | 2.3% | 126 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.