Gene
CDC42
cell division cycle 42
Explore in graph →CI-GENE-00040624HGNC:1736 ENSG00000070831 NCBI 998 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38630790
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pleural Mesothelioma (MSK, Clin Cancer Res 2024) plmeso_msk_2024 | Pleural Mesothelial Neoplasm | Ssm | 1 | 12 | 8.3% | 16 | cbioportal |
| MAPK on resistance to anti-HER2 therapy for breast cancer (MSK, Nat Commun. 2022) brca_mapk_hp_msk_2021 | Invasive Breast Carcinoma | Ssm | 1 | 61 | 1.6% | 119 | cbioportal |
| Gastrointestinal Stromal Tumors (MSK, Clin Cancer Res 2023) gist_msk_2023 | Gastrointestinal Stromal Tumor | Ssm | 1 | 342 | 0.3% | 108 | cbioportal |
| Gastrointestinal Stromal Tumor (MSK, NPJ Precis Oncol 2023) gist_msk_2022 | Gastrointestinal Stromal Tumor | Ssm | 1 | 374 | 0.3% | 114 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.