Gene
CCDC66
coiled-coil domain containing 66
Explore in graph →CI-GENE-00032551HGNC:27709 ENSG00000180376 NCBI 285331 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (TCGA, Firehose Legacy) dlbc_tcga | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 4 | 48 | 8.3% | 130 | cbioportal |
| Pancreatic Cancer (UTSW, Nat Commun 2015) paad_utsw_2015 | Pancreatic Adenocarcinoma | Ssm | 4 | 109 | 3.7% | 90 | cbioportal |
| Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014 | Thymus Epithelial Neoplasm | Ssm | 1 | 32 | 3.1% | 86 | cbioportal |
| Pancreatic Neuroendocrine Tumors (Multi-Institute, Nature 2017) panet_arcnet_2017 | Pancreatic Neuroendocrine Tumor | Ssm | 2 | 98 | 2% | 56 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.