Gene
CCDC27
coiled-coil domain containing 27
Explore in graph →CI-GENE-00032522HGNC:26546 ENSG00000162592 NCBI 148870 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33863915
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metaplastic Breast Cancer (MSK,NPJ Breast Cancer 2021) mbc_msk_2021 | Breast Metaplastic Carcinoma | Ssm | 1 | 5 | 20% | 90 | cbioportal |
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 6 | 75 | 8% | 130 | cbioportal |
| The Angiosarcoma Project (Provisional, July 2020) angs_painter_2020 | Angiosarcoma | Ssm | 6 | 83 | 7.2% | 151 | cbioportal |
| The Angiosarcoma Project - Count Me In (Provisional, April 2025) angs_painter_2025 | Angiosarcoma | Ssm | 7 | 129 | 5.4% | 42 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.