Gene
CAPN6
calpain 6
Explore in graph →CI-GENE-00032290HGNC:1483 ENSG00000077274 NCBI 827 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 30867592
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Histiocytosis Cobimetinib (MSK, Nature 2019) histiocytosis_cobi_msk_2019 | Histiocytic and Dendritic Cell Neoplasm | Ssm | 1 | 15 | 6.7% | 69 | cbioportal |
| Breast Fibroepithelial Tumors (Duke-NUS, Nat Genet 2015) bfn_duke_nus_2015 | Breast Fibroepithelial Neoplasm | Ssm | 1 | 22 | 4.5% | 50 | cbioportal |
| Adrenocortical Carcinoma (TCGA GDC, 2025) acc_tcga_gdc | Adrenal Cortical Carcinoma | Ssm | 3 | 90 | 3.3% | 95 | cbioportal |
| Adrenocortical Carcinoma (TCGA, PanCancer Atlas) acc_tcga_pan_can_atlas_2018 | Adrenal Cortical Carcinoma | Ssm | 3 | 91 | 3.3% | 142 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.