Gene
C5
complement C5
Explore in graph →CI-GENE-00031911HGNC:1331 ENSG00000106804 NCBI 727 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26829750
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (MGH, Nat Gen 2016) acyc_mgh_2016 | Adenoid Cystic Carcinoma | Ssm | 2 | 10 | 20% | 40 | cbioportal |
| Metastatic Prostate Adenocarcinoma (MCTP, Nature 2012) prad_mich | Prostate Adenocarcinoma | Ssm | 2 | 61 | 3.3% | 165 | cbioportal |
| Breast Cancer (SMC 2018) brca_smc_2018 | Invasive Breast Carcinoma | Ssm | 3 | 186 | 1.6% | 128 | cbioportal |
| Kidney Chromophobe (TCGA, Cancer Cell 2014) kich_tcga_pub | Chromophobe Renal Cell Carcinoma | Ssm | 1 | 65 | 1.5% | 182 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.