Gene
C2
complement C2
Explore in graph →CI-GENE-00031844HGNC:1248 ENSG00000166278 NCBI 717 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28927585
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Adenocarcinoma (SMMU, Eur Urol 2017) prad_eururol_2017 | Prostate Adenocarcinoma | Ssm | 2 | 65 | 3.1% | 16 | cbioportal |
| Chronic lymphocytic leukemia (ICGC, Nature Genetics 2011) cllsll_icgc_2011 | Small Lymphocytic Lymphoma | Ssm | 1 | 105 | 1% | 162 | cbioportal |
| Myeloproliferative Neoplasms (CIMR, NEJM 2013) mpn_cimr_2013 | Myeloproliferative Neoplasm | Ssm | 1 | 151 | 0.7% | 151 | cbioportal |
| Papillary Thyroid Cancer (TCGA GDC, 2025) thpa_tcga_gdc | Thyroid Gland Papillary Carcinoma | Ssm | 2 | 496 | 0.4% | 189 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.