Gene
BRAT1
BRCA1 associated ATM activator 1
Explore in graph →CI-GENE-00022041HGNC:21701 ENSG00000106009 NCBI 221927 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24121792
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Bladder Urothelial Carcinoma (BGI, Nat Genet 2013) blca_bgi | Bladder Urothelial Carcinoma | Ssm | 3 | 99 | 3% | 192 | cbioportal |
| Medulloblastoma (Broad, Nature 2012) mbl_broad_2012 | Medulloblastoma | Ssm | 1 | 92 | 1.1% | 198 | cbioportal |
| Pediatric Acute Myeloid Leukemia (TARGET, 2018) aml_target_2018_pub | Acute Myeloid Leukemia | Ssm | 1 | 150 | 0.7% | 76 | cbioportal |
| Myeloproliferative Neoplasms (CIMR, NEJM 2013) mpn_cimr_2013 | Myeloproliferative Neoplasm | Ssm | 1 | 151 | 0.7% | 143 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.