Gene
AURKC
aurora kinase C
Explore in graph →CI-GENE-00021489HGNC:11391 ENSG00000105146 NCBI 6795 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22343534
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Diffuse Large B-Cell Lymphoma (Broad, PNAS 2012) dlbc_broad_2012 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 3 | 58 | 5.2% | 154 | cbioportal |
| Acute Myeloid Leukemia (TCGA GDC, 2025) aml_tcga_gdc | Acute Myeloid Leukemia | Ssm | 1 | 72 | 1.4% | 55 | cbioportal |
| Meningioma (University of Toronto, Nature 2021) mng_utoronto_2021 | Meningioma | Ssm | 1 | 115 | 0.9% | 190 | cbioportal |
| Miscellaneous Neuroepithelial Tumor (TCGA GDC, 2025) mnet_tcga_gdc | Central Nervous System Neuroepithelial Neoplasm of Uncertain Origin | Ssm | 1 | 183 | 0.5% | 193 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.