Gene
ASIC3
acid sensing ion channel subunit 3
Explore in graph →CI-GENE-00011536HGNC:101 ENSG00000213199 NCBI 9311 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Refractory Cancers (RC) - Peripheral T-Cell Lymphoma (PTCL) RC-PTCL | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Ssm | 16 | 58 | 27.6% | 38 | gdc |
| Cholangiocarcinoma (National Cancer Centre of Singapore, Nat Genet 2013) chol_nccs_2013 | Cholangiocarcinoma | Ssm | 1 | 15 | 6.7% | 26 | cbioportal |
| Ewing Sarcoma (Institut Curie, Cancer Discov 2014) es_iocurie_2014 | Ewing Sarcoma | Ssm | 1 | 112 | 0.9% | 113 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.