Gene
ASAH2
N-acylsphingosine amidohydrolase 2
Explore in graph →CI-GENE-00011473HGNC:18860 ENSG00000188611 NCBI 56624 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29033130
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Melanoma (MSK, Cell 2017) - iAtlas Harmonized mel_iatlas_riaz_nivolumab_2017 | Melanoma | Ssm | 8 | 73 | 11% | 122 | cbioportal |
| Intrahepatic Cholangiocarcinoma (JHU, Nat Genet 2013) chol_jhu_2013 | Cholangiocarcinoma | Ssm | 1 | 40 | 2.5% | 190 | cbioportal |
| Chromophobe Renal Cell Carcinoma (TCGA GDC, 2025) chrcc_tcga_gdc | Chromophobe Renal Cell Carcinoma | Ssm | 1 | 66 | 1.5% | 187 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.