Gene
ARHGAP6
Rho GTPase activating protein 6
Explore in graph →CI-GENE-00011192HGNC:676 ENSG00000047648 NCBI 395 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26928463
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Adenocarcinoma (Fred Hutchinson CRC, Nat Med 2016) prad_fhcrc | Prostate Adenocarcinoma | Ssm | 7 | 141 | 5% | 189 | cbioportal |
| Metastatic Breast Cancer (INSERM, PLoS Med 2016) brca_igr_2015 | Invasive Breast Carcinoma | Ssm | 6 | 216 | 2.8% | 141 | cbioportal |
| Acute Myeloid Leukemia (TCGA, PanCancer Atlas) laml_tcga_pan_can_atlas_2018 | Acute Myeloid Leukemia | Ssm | 3 | 200 | 1.5% | 161 | cbioportal |
| Acute Myeloid Leukemia (TCGA GDC, 2025) aml_tcga_gdc | Acute Myeloid Leukemia | Ssm | 1 | 72 | 1.4% | 41 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.