Gene
ARHGAP4
Rho GTPase activating protein 4
Explore in graph →CI-GENE-00011189HGNC:674 ENSG00000089820 NCBI 393 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (11)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32888432
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (CAS Shanghai, Cancer Cell 2020) coadread_cass_2020 | Colorectal Adenocarcinoma | Ssm | 12 | 146 | 8.2% | 126 | cbioportal |
| Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017 | Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type | Ssm | 1 | 16 | 6.3% | 145 | cbioportal |
| Classical Hodgkins Lymphoma (SCCC, Blood Cancer Discov 2023) chl_sccc_2023 | Classic Hodgkin Lymphoma | Ssm | 3 | 61 | 4.9% | 131 | cbioportal |
| Cervical Squamous Cell Carcinoma (TCGA GDC, 2025) cesc_tcga_gdc | Cervical Squamous Cell Carcinoma | Ssm | 13 | 289 | 4.5% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.